Search Dotmatics Bioregister for a Similar Sequence

Click on File → Import → Dotmatics Bioregister Sequences  to start a search for a sequence.

Alternatively, on the SnapGene top toolbar click Import → Dotmatics Bioregister Sequences.

Select Search Dotmatics Bioregister for to Sequence and type or copy and paste a sequence into the Sequence field.

Select an area of interest in an open SnapGene file and click Tools → BLAST Selected Sequence in Bioregister → DNA Database (alternatively, RNA or Protein database):

The system pre-populates a Sequence field from the selection:

Choose whether to search the DNA, Protein or RNA database.

If necessary change sorting criteria based from E-value (default) to Score, Identity, Positives or Gap.

Click on Search Bioregister button.

For every sequence "hit" detected in Bioregister, view the following information:

• Bioregister ID and Name
• Similarity parameters (Score, E-value, Identities, Positives, Gaps)

View or hide individual hit alignments by toggling the disclosure buttons.

Select one or more sequences of interest by selecting a checkbox.

Select Open and click on the Import button to open the selected sequences in SnapGene. The Accession Number field in the Description Panel will contain the Bioregister ID. Please note, that the standard Accession Number link points to the NCBI database and not Dotmatics Bioregister.

Alternatively, select Save and click on the Import button to save a sequence to disk. The system will ask to select an appropriate location to save the files.